New genetic cause of pulmonary hypertension identified

[unable to retrieve full-text content]Scientists have identified new genetic mutations that can cause pulmonary arterial hypertension (PAH), a rare fatal disease characterized by high blood pressure in the lungs. The mutations, found in the gene KCNK3, appear to affect potassium channels in the pulmonary artery, a mechanism not previously linked to the condition. Cell culture studies showed that the mutations? effects could be reversed with a drug compound known as a phospholipase inhibitor.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/bK6LRS1rcsg/130724195942.htm

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